Injuries can happen any time. Accidents are an integral part of this life. We grow up bumping, stumbling and colliding into things until we’re wearing bruises, scabs and scars as comfortably as we wear our clothes. It’s that preparation as we grow up that helps us avoid them when we’re older which is why it seems that the injuries we do suffer from are even worse than those that we had when we were younger. Last year I fell right off a ladder that I was using while working. I arrived at the San Jose accident injury chiropractor – the last place I thought that I would ever end up at. Continue reading →
When I was younger, my parents were one of the few people I knew who saw a chiropractor on a regular basis. They still see one, and I have followed their trend in doing so. While it is a lot more popular now, I do it because I have seen how my parents have taken care of their health and their bodies over the last 30 years. Going to a San Jose chiropractor has really helped them with various issues, and they are healthier than most people their age. I attribute a lot of that to the careful decisions they have made over the years.
I made my first appointment when I was in high school because I played a lot of sports. Continue reading →
My mom was involved in an accident several years ago. She did receive treatment for her injuries, but she never fully recovered from them. We thought that it was just something that she was going to have to live with the rest of her life, and that made my brothers and I very upset. Mom took it in great stride though, and she rarely complained about how she was feeling. I was talking with a friend about it after Mom had a bad day, and she told me that Mom should see her chiropractor in Bakersfield CA.
She had already been to two different doctors, and they had both told her that physical therapy was the answer. Continue reading →
Acne seems to be the great equalizer. It’s the one condition that almost everyone suffers from at some point in his or her life. An acne breakout can cause you to lose confidence in yourself, and if not treated properly, it can actually cause serious long-term damage to the skin. While claims on TV commercials or magazine ads sound fabulous, does this acne treatment really work? Read this article to find out. If you have acne, you’ve probably seen TV commercials or magazine ads for various acne treatments. Of course, each ad claims that their acne treatment product is the best. You’ll see bold claims like: Enjoy clear skin in just 3 days! or Never suffer another breakout again! And while these claims certainly sound nice, you have to wonder if they’re really true. In short, does acne treatment really work? Or is it a big scam? Keep reading to find out the truth. Natural Acne Treatment Natural acne treatment products have become an increasingly popular alternative to prescription treatments. These natural treatments use various herbs to kill acne-causing bacteria and to improve overall skin quality. Natural acne treatment typically consists of tea tree oil, black seed currant oil, echinacea, and goldenseal, to name just a few. The main reason people are attracted to these natural treatments is because they’re convenient and affordable. They typically tend to be gentler than prescription treatments; although, they can take longer to produce results. Before you purchase any natural acne treatment, make sure to spend time reading reviews online so that you understand which products work best. Homemade Acne Treatment When desperate to get rid of acne, some people will try anything. That’s where a homemade acne treatment enters the picture. Home acne treatments are cheap and accessible alternatives to creams and skin cleaning products. A few examples of homemade acne treatments include: • Lemon juice • Natural oatmeal remedy • Aloe Vera While it might sound appealing to make your own acne treatment at home, the truth is these treatments are typically ineffective. And for the rare treatment that actually does work, it tends to take much longer (6 months in some cases) to go into effect. There are acne treatment alternatives that are more convenient and more effective than homemade acne treatment. Best Acne Treatment When you have pimples and serious breakouts, you just want to find the best acne treatment available so you can eliminate the problem and move on with your life. The best way to find the right acne treatment for your needs is to spend some time reading expert reviews of different products online. Acne treatment reviews give you insight into which products work and which ones don’t. You’ll also discover which ingredients to look for in acne treatments and how much you can expect to pay for the best acne treatment. RevitaClear RevitaClear is a comprehensive acne treatment system that has gotten many positive reviews. The RevitaClear system consists of a facial wash, a moisturizing lotion, and an acne spot treatment. Together, these products work to eliminate acne-causing bacteria, to smooth out affected skin, and to help prevent acne from coming back. Learn more about RevitaClear acne treatment today!
When it pertains to treatment for herpes there are not many subjects who are as under discussed within a society as the difference between episodic and suppressive treatment. To comprehend episodic and suppressive treatment we firstly have to examine a little the herpes simplex virus life cycle. After the original contamination (that is ordinarily by means of direct skin contact with a viral shedding region) the herpes virus goes deep into our bodies and hides inside a specific part of the nervous system – based on where the first infection took place. In roughly 2 to 20 days(typically) once this original contamination takes place an outbreak erupts. During this stage the virus starts aggressively multiplying and making its way towards the outbreak location. It overwhelms the immune system by way of sheer numbers and you begin showing some of the outward symptoms of herpes – the oozing sores. Now, episodic treatment for herpes simply means you will only use measures against the virus in the course of this outbreak – or, if you catch on, during the prodrome. What you are doing at this point is basically attacking the virus after it has begun to mount the assault against you – which also coincides with a period of bodily weakness for you. This means that your body is weak and that you are helping it out in battling the virus. However, the draw back of this is that our bodies can not win the struggle, it can merely drive the virus back. The virus then lies hidden and waits for another opportunity to attack. This is why suppressive treatment for herpes is better and why more people should look at it. Suppressive treatment means that you are consistently taking action designed to keep the herpes virus in check. This treatment also offers the advantage that if an outbreak does happen, you’re more able to cope with it. The virus is forced back faster AND many people think that it could even be diminished in terms of number of copies present in the body. This basically implies that over time you would possibly have a chance to eradicate all the copies of the virus from your system. This has not been proved however and the fact of the matter is that these individuals each employ a different treatment for herpes. There are no shortcuts and you should get educated. Herpes treatment is a quite active field with lots of people fueling the flames. What you ought take with you: In the event you have herpes, there is hope. What you need to do is make the best using what you’ve got at the moment and keep an eye out for promising therapies for the future. In the event you would like to understand more on the subject of what is presently available as a treatment for herpes as well as stay updated on the newest findings on this virus, visit us at: Treatment For Herpes
Hemochromatosis, or as it is often referred to as hereditary hemochromatosis, is due to a mutation in a gene that controls the amount of iron absorbed from the intestine.
The gene mutated with hereditary hemochromatosis is called HFE. Each parent contributes the HFE gene. The HFE gene has two common mutations, C282Y and H63D.
If a patient inherits two mutated HFE genes, the likelihood is very high, they will get hemochromatosis.
If one abnormal gene is inherited, the likelihood is the patient won’t develop hemochromatosis.
Still the amount of iron absorbed from the intestine may be a bit higher than normal and the mutated gene can be passed on to children.
Genetic testing can detect mutations in the HFE gene.
Normally, about 10 per cent of iron is absorbed from the gut. There is a balance the body establishes so that iron absorption is controlled by iron loss.
In people with hemochromatosis, the amount of iron absorbed can be 20-30 per cent making it impossible for the body to get rid of enough iron. Iron accumulates in various organs including the liver, heart, pancreas, and joints.
Risk factors for contracting hemochromatosis are: genetics, family history, Northern European extraction, and male gender. After menopause, women tend to have an increased incidence as well. It appears that menstruation may be protective premenopausal. Symptoms include fatigue, joint aches and pains, impotence, loss of menses, and abdominal pain.
Diagnosis can be established through screening blood tests such as serum transferrin saturation and serum ferritin.
Liver biopsy is definitive.
Genetic analysis can detect the HFE mutation.
Complications of hemochromatosis include cirrhosis of the liver, heart abnormalities such as rhythm abnormalities and congestive heart failure, as well as thyroid deficiency, diabetes and arthritis. Patients develop discoloration of the skin also.
Arthritis is present in 80 per cent of people with hemochromatosis.
The arthritis is characterized by involvement of the hands, wrists, shoulders, hips, and knees. People with this type of arthritis almost always have calcium pyrophosphate deposits in the affected joints. The arthritis is usually not symmetric. It can mimic osteoarthritis and rheumatoid arthritis.
The treatment for this type of arthritis is identical to treatment for other patients who have calcium pyrophosphate arthritis.
Treatment of hemochromatosis involves phlebotomy as well as avoidance of iron-containing foods, vitamin C which enhances iron absorption, alcohol, as well as raw seafood. The latter contains potentially harmful bacteria that can cause life-threatening complications in patients with hemochromatosis.
Elevated iron study results are a frequent laboratory finding that can be a clue to a common genetic disorder. Hereditary hemochromatosis is an inherited disorder of iron metabolism that can cause organ damage from the accumulation of excess iron (1, 2). The most common form of hereditary hemochromatosis (“hemochromatosis type 1”) results from mutations in the gene known as HFE. The specific mutations associated with hereditary hemochromatosis are the substitution of a tyrosine for cysteine at amino acid 282 (C282Y) and the substitution of aspartic acid for histidine at amino acid 63 (H63D) (1, 2). Individuals who are homozygous for the C282Y mutation or who have single copies of both the C282Y and H63D mutations (compound heterozygotes) are susceptible to developing iron overload, with 85% to 90% of hemochromatosis cases occurring in C282Y homozygotes and the remainder occurring in compound heterozygotes (1, 3, 4). In contrast, simple C282Y heterozygotes and H63D heterozygotes and homozygotes are not at risk for hereditary hemochromatosis (2, 4, 5). Additional forms of primary iron overload (hemochromatosis types 2-4) caused by mutations in iron-regulatory genes other than HFE are now recognized (1, 2) but genetic testing for these rare conditions is not routinely available.
Multiple conditions can be associated with abnormal iron study results in the absence of an inherited defect in iron metabolism (6). Secondary abnormalities of iron tests are frequently seen in the context of hematologic diseases, in particular hemolytic anemias, anemia secondary to ineffective erythropoiesis, and disorders treated with multiple transfusions, and in several common types of chronic liver disease. Among the latter group, increased iron studies are seen in up to 50% of patients with alcoholic liver disease, nonalcoholic fatty liver disease, or chronic viral hepatitis (4). In this setting, elevations in transferrin saturation or serum ferritin levels do not invariably reflect the presence of excess iron in the liver or other organs. The clinical significance of elevated iron study results and hemosiderosis in liver disease-and whether this condition requires treatment-remains controversial (6). This contrasts with hereditary hemochromatosis and transfusional iron overload, in which there is consensus that heavy iron loading causes organ damage and that removal of excess iron can prevent these complications (7, 8, 9). Thus, correct identification of the cause of iron test abnormalities is required to determine appropriate treatment.
The identification of the HFE mutations in 1996 was a major step toward improving the accuracy of diagnosis of hereditary hemochromatosis (7). In view of the high prevalence of conditions associated with secondary abnormalities of iron metabolism, HFE genotyping is a useful tool to distinguish hereditary hemochromatosis from these secondary abnormalities. The aims of this study were to investigate the approach of physicians to elevated iron study results at an academic medical center, to assess the accuracy of their diagnoses of hereditary hemochromatosis, and to identify factors that contribute to misdiagnosis.
Material & Methods:
The institutional review board of the University of Iowa approved this study. A list of patients seen at the University of Iowa between January 2002 and May 2006 and between January 2009 and May 2012 with the International Classification of Diseases (ICD) 9th Revision code 275 “disorders of iron metabolism” as a primary or secondary diagnosis was obtained. Patients seen between 2006 and 2009 were not included because transition to a new electronic medical record occurred during this period. A systematic review of the electronic medical records was then performed. Patients with iron deficiency were excluded.
Subjects with no mention of iron overload and no findings in their records suggesting abnormal iron metabolism were considered to be miscoded and were likewise excluded from the study. For patients included in the study, the following data were collected: age at diagnosis, gender, family history of hereditary hemochromatosis, HFE genotype, history of multiple transfusions or known hematologic disease, or evidence of chronic liver disease. Diagnoses of cirrhosis or hepatocellular carcinoma based on clinical findings or imaging or pathology results, and recommendations for or records of phlebotomies were tabulated. The specialty of the diagnosing provider, the year of diagnosis, and the laboratory studies corresponding to that visit were recorded. Laboratory studies included iron levels, total iron-binding capacity, transferrin saturation, ferritin level, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase, and total bilirubin.
The 2011 practice guidelines of the American Association for the Study of Liver Disease were used to assess the appropriate diagnostic strategy and management of hereditary hemochromatosis.4 Transferrin saturation level >45% and ferritin level >250 ng/mL in women and >300 ng/mL in men were considered elevated. Aspartate aminotransferase and alanine aminotransferase >1.5 times the upper limit of normal, which corresponds to 50 U/L in our facility, were considered elevated.
An analysis was done to compare the characteristics of those diagnosed between 2002 and 2006 with those diagnosed between 2009 and 2012. Because the continuous data were not normally distributed, we presented them as medians and interquartile range and used the Wilcoxon rank-sum test to detect statistical significance. For categoric variables, the chi-square test was used. Statistical significance was set at P 45% or increased ferritin (4). One third of patients meeting these criteria in our study did not have a documented HFE genotype. Several factors may contribute to the failure to obtain genetic testing. One is the presence of an obvious cause of secondary iron test abnormalities, which was present in many of the patients who were not genotyped. Whether a decision to forego genotyping in this situation is justified depends on the clinical context, but this does not account for the lack of HFE genotyping in those patients without an obvious cause of secondary iron test abnormalities. Another possibility might be the misconception that elevated iron parameters are unlikely to be a sign of hemochromatosis in the absence of the classic findings of “bronze diabetes,” which are rarely seen (7). Ultimately, the finding that 35% of the patients without a documented HFE genotype were nonetheless diagnosed with hereditary hemochromatosis reflects a knowledge deficit regarding the diagnostic criteria for this condition. Although genetic testing may have been performed elsewhere in some cases, it is doubtful that this was a frequent occurrence, given that neither that information nor external genotyping results were documented in the chart, despite a decision to initiate treatment. These findings are consistent with a previous report suggesting that primary care physicians use HFE testing less frequently than do subspecialty physicians (10).
HFE genotyping is frequently misinterpreted. In our series, hereditary hemochromatosis was diagnosed incorrectly in more than half of the patients with nonhereditary hemochromatosis genotypes. More than two thirds of these misdiagnoses were made by nonspecialists, indicating confusion in the interpretation of HFE genotyping. Several factors may contribute to this confusion. At our institution, HFE genotyping returns with a fairly lengthy description of the testing methodology and its interpretation. Some providers may fail to read the entire report and interpret the presence of a single mutation as diagnostic of hemochromatosis. Further compounding the potential for misdiagnosis is the fact that even in the heterozygous state, the C282Y and H63D mutations can be associated with modest increases in iron parameters (11). Thus, without specific knowledge that these genotypes are not causes of hereditary hemochromatosis, misdiagnosis of hemochromatosis in these circumstances is an understandable error.
Awareness of common causes of secondary iron test abnormalities, in particular chronic liver disease, is low. Patients with nonhereditary hemochromatosis genotypes who present with abnormal iron study results should be carefully investigated for secondary causes of abnormal iron metabolism (4). Non-HFE hereditary hemochromatosis (hemochromatosis type 2-4) should be on the differential in those patients, although these conditions are rare. Among the patients with nonhereditary hemochromatosis genotypes in whom hemochromatosis was correctly ruled out, approximately 90% had a well-defined cause for abnormal iron study results. On the other hand, we were able to retrospectively identify an explanation for abnormal iron study results in approximately three quarters of the misdiagnosed group. In nearly all of those cases, risk factors for chronic liver disease were present, but chronic liver disease had not been recognized as a potential cause of iron test abnormalities. Of note, hematologic causes of secondary iron overload posed little confusion, and most cases of hemolytic anemia, anemia secondary to ineffective erythropoiesis, and history of multiple transfusions were readily recognized as causes of abnormal iron study results. Chronic liver disease was far more common in this study than were hematologic disorders. It seems that many primary care providers may be unaware of the association of elevated iron study results with chronic liver disease. Further compounding the potential for misdiagnosis, iron studies are commonly obtained in the course of evaluation of elevated aminotransferases. In this setting, elevated iron parameters are frequently assumed to be the cause, rather than the consequence, of the underlying liver disease. However, hereditary hemochromatosis is not commonly associated with increased level of liver enzymes, as demonstrated by a recent study showing that the probability of diagnosing hemochromatosis in patients with hyperferritinemia decreases with increased aspartate aminotransferase and alanine aminotransferase levels (12). Our observation that only 18% of patients with hereditary hemochromatosis alone had abnormal liver enzymes is consistent with these findings.
Consequences of Misdiagnosis
Some 38% of the patients with nonhereditary hemochromatosis genotypes and an unknown proportion of those who were not genotyped were treated inappropriately with phlebotomy. Not only is de-ironing not indicated in the absence of an appropriate hereditary hemochromatosis genotype with evidence of expanded body iron stores (4, 13) but also the aggressive phlebotomy regimens used in the treatment of hemochromatosis are potentially harmful. Phlebotomy is not without risks and, if used inappropriately, can cause iron deficiency anemia and fatigue, in addition to psychologic and financial burdens. Of equal importance, an incorrect diagnosis of hereditary hemochromatosis can be a distraction that prevents identification of the actual cause of abnormal iron study results, thereby delaying appropriate treatment.
The appropriate evaluation and management of abnormal iron study results is an area that requires better understanding and knowledge, especially among nonspecialists. Patients with elevated transferrin saturation or ferritin without an obvious cause should be tested for HFE mutations. The HFE genotypes that can cause hereditary hemochromatosis with manifestations of iron overload are C282Y/C282Y and C282Y/H63D (7). All patients in whom the diagnosis of hereditary hemochromatosis is considered should have an HFE genotype documented before treatment with phlebotomy. We suggest that this information be required by the phlebotomy centers before initiation of treatment. Patients with abnormal iron study results and nonhereditary hemochromatosis genotypes should be investigated for other causes of abnormal iron metabolism with particular attention to chronic liver diseases, which are a frequently unrecognized cause of abnormal iron study results. Specialist consultation should be sought for assistance with diagnosis and management.
One of the prime reasons for getting liver transplants across the world is Cirrhosis. Liver fails of function properly due to permanent or long-term damages in Cirrhosis. The healthy tissues of the liver are damaged and are replaced by scar tissue.
Some of the common causes of failure of the liver are alcoholism, drugs such as Paracetamol and Isoniazid. Other causes of liver failure are Sero-Negative Hepatitis, Viral hepatitis B, Viral hepatitis C, Autoimmune Hepatitis, and Cryptogenic cirrhosis. Wilson’s disease and Hemochromatosis are some of the metabolic causes that permanently damage the liver.
It is advisable to undergo transplant of the liver in cases of Cirrhosis as the life expectancy of the patients is reduced to nearly one year if left untreated. As per the advanced Model for End-stage Liver Disease (MELD), the severity of liver damage can be graded from A to C. Where the cases of A Grade can be effectively treated through medications but the cases of Grade C and most of Grade B requires transplantation of healthy liver as soon as possible.
Early detection can be helpful in controlling the symptoms through medications or endoscopic therapy, but later stages of these complications require successful liver transplant within stipulated time frame. Due to the advancement of technology, it was reported the most of the liver transplantation in India are successful. As per the report, it was reported that about 95% of the transplantation of liver are successful in India. Most of the failed cases were reported to be caused due to liver cancer and biliary complication.
Due to high success rate, low cost of medication & surgery and fast recovery, many cities in India are ideal for liver transplantation. Chennai, Delhi, Mumbai, and Kolkata, are some of the cities where the patients can go for successful liver transplantation at cost effective prices and extremely high success rate.
Around 40-50 % of the patients across India visits Chennai for getting different types of medical care services. With more than 175-200 international patients getting treatment daily, Chennai is considered to be health capital of India. It was reported that more than 2 billion dollars were generated from medical/health tourism in the year 2015, in which Chennai played very important role.
The multi-specialty hospitals in Delhi with world-class infrastructure and a team of skilled transplant surgeons render best possible liver transplantation in Delhi. With experience and knowledge of liver transplants, the best Liver Transplant Surgeon in Delhi has effective done more than thousands successful liver operations.
The complex Liver Transplant that involves liver, pancreas, and bile ducts, requires surgeons with expertise in the field of Hepato Pancreatico Biliary (HPB) Surgery.
Hemochromatosis is an extremely dangerous disease, since it can affect a number of organs, lead to lower life expectancy, and in some cases – cause death. Fortunately, keeping a good diet will keep most of the symptoms away. There is also a new natural cure, which has proven to be extremely effective for reversing hemochromatosis.
One of the main thing, which you should avoid if you have too much iron in the blood is red meat. Other animal products also pose a hazard. That’s why it is best to cure the condition and then be able to eat a rich diet. The diet that is required to completely remove any symptoms of hemochromatosis will negatively affect your body. It’s a trade-off. But there is a third option – get rid of the disease. Up until 2009, we thought that hemochromatosis is not curable – only treatable and manageable. Now we know that is not true – there is a natural way to reverse the disease, provided that you follow certain principles.
Your body is the only thing, which can get rif of too much iron in the blood. That’s what a natural treatment enables it to do. As you know, there are many conditions which we cannot cure directly. But what we CAN do is to enable your own body to cure them on it’s own. That’s how we deal with viral diseases for example. Iron overload is no different, and it has a very specific cause. People who have this disease have a certain deficiency of proteins, and that can be easily solved. That’s one of the reasons why not eating meat and keeping a hemochromatosis diet often makes the disease worse, despite your doctor’s advice. That’s why it is best to think on your own when it comes to your own health, and not blindly follow the advice of doctors.
When the natural form of treatment is applied, the symptoms disappear, and your liver will be able to process iron easily again. That can happen very quickly, or in a couple of days, depending on your metabolism and or whether or not you have other underlying liver diseases.
Maintaining Discipline in hair force
When the child stays at home all day, and mommy is the teacher,
there are certain issues of discipline at stake. It is easy for he
child to misconstrue the freedom he has at home and feel that
homeschooling is just a long summer holiday. This is a potential hair force
landmine and children need to be disciplined right at the start.
Homeschooling gives you and your child a truly immense amount of
flexibility. You and your child decide where to learn, how much to
learn and when to learn. But,these should be decisions made at
the beginning stages. If your child is too little to take an
active part in the decision, chart out a few hours of the day for grey away
the various activities, and stick to it. When there is no outside hair force
agency to supervise and no exams to answer, it is easy to get
sidetracked. If your child is old enough, consult him and find out
when he wants to learn. Apply your parental discretion and come up
with a timetable.
Homework is also a part of homeschooling. What this means is that
once lessons have been taught, the child should be asked to do
some part of the course work by himself without your guidance. You
will need to make sure that your child sits willingly and finishes hair force
Courtesy, manners and punctuality are some of the various facets
of discipline that a child has to imbibe in the early years of his
life. The school where he interacts with his peers, his seniors
and juniors and his teachers mould these values quite
automatically. At homeschool, the child should be taught the grey away
importance of speaking and behaving in a proper manner and
appropriate corrections need to be meted out if behavior is hair force
It is advisable to keep aside a particular room or a part of the
room for your homeschool. The child should be expected to reach
his desk at the appointed time, in proper attire with all the
necessary material. It is easy to allow the school to become an grey away
extension of play if these ground rules are not laid out and
followed. As the teacher, supervisor, principal and janitor rolled
into one, you should also approach the study area with a cool
Homeschooling is doomed to fail without patience. In spite of all grey away
the precautions and steps one takes, it is easy for a child to get
familiar’ at homeschool. At such times, it may be difficult to hair force
discipline the child and get him to listen to you attentively.
When this happens, switch to something new. Allow the child to Traitements cheveux
take a breather and enjoy a break yourself.
Homeschooling is not easy. It requires a lot of hard work and
patience. The very informality of the whole procedure sometimes grey away
works against it by making it too easy. If you take steps to hairrebirth
establish rules at the very beginning and adhere to these rules, hair force
your homeschooling experience will be a huge success.